Saturday, May 4, 2013

Nature. 2012 May 10;485(7397):251-5.


Nature. 2012 May 10;485(7397):251-5. doi: 10.1038/nature10992.

Mitochondrial DNA that escapes from autophagy causes inflammationand heart failure.

Oka T, Hikoso S, Yamaguchi O, Taneike M, Takeda T, Tamai T, Oyabu J, Murakawa T, Nakayama H,Nishida K, Akira S, Yamamoto A, Komuro I, Otsu K.

Source

Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, Japan.

In Fig. 4d, the panel showing CD3 staining for ODN2088 control-treated TAC-operated Dnase2a+/+ mice is a duplicate of that showing Ly6G staining for ODN2088-treated TAC-operated Dnase2a−/− mice. 
































大阪大学大学院医学系研究科 循環器内科学 Nature誌論文 Fig.4d 最下段(CD3)の一番左の画像が、上から3段目(Ly6G)の一番右の画像と同一。 ケアレスミスか?念のため、他にも調査の必要性があるか?

 (その後、Corrigendum が出される。指摘の件以外にも、多数の不適切な画像操作が判明)
↓ 

Erratum in


Nature. 2012 Oct 11;490(7419):292.


In this Letter, several images were mistakenly switched or duplicated during preparation of the artwork. In Figs 1f and 2a, the sham-operated Dnase2a−/− and TAC-operated Dnase2a+/+ mice panels were switched. In Fig. 4d, the panel showing CD3 staining for ODN2088 control-treated TAC-operated Dnase2a+/+ mice (now shown correctly as black-bordered panel in Fig. 1 below) is a duplicate of that showing Ly6G staining for ODN2088-treated TAC-operated Dnase2a−/− mice. The panel showing CD45 staining for ODN2088-treated TAC-operated Dnase2a+/+ (now shown correctly as blue-bordered panel in Fig. 1 below) was prepared from the original picture of ODN2088 control-treated TAC-operated Dnase2a+/+. In Supplementary Fig. 4c, sham-operatedDnase2a−/− and TAC-operated Dnase2a+/+ mice panels were switched. Finally, in Supplementary Fig. 10d, the panels showing CD3 and Ly6G staining for sham-operated Tlr9+/+ mice were switched. These corrections do not alter any of the conclusions of this Letter, and the authors apologize for any confusion these errors may have caused.

大阪大学医学系グループが不適切研究! (ブログ 世界変動展望)




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