Nature. 2008 Jul 17;454(7202):345-9. doi: 10.1038/nature07027. Epub 2008 Jun 4.
IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis.
Zhu W, Shiojima I, Ito Y, Li Z, Ikeda H, Yoshida M, Naito AT, Nishi J, Ueno H, Umezawa A, Minamino T, Nagai T,Kikuchi A, Asashima M, Komuro I.
Source
Department of Cardiovascular Science and Medicine, Chiba University Graduate School of Medicine, Chiba 260-8670, Japan.
(The above PDF file has higher resolution images compared with the html file。）
In the beta-actin panel of Fig.1C, a left band (OP-9) is similar to a right band (OP-9 + anti-BP4).
Concern#2
In the beta-Actin panel of Fig.3B, lane 1 and lane 2 bands from the left are similar.
In the beta-Actin panel of Fig.3B, lane 1 and lane 2 bands from the left are similar.
Concern#3
In Fig.3e, lane 3 and 5 bands from the left of a "alpha-MHC" panel are inappropriately erased, and Lane 1, 4 and 6 of the "alpha-MHC" panel and lane 5 of a "GATA-4" panel are similar to each other.
Concern#4
In the "GATA-4" panel of Fig.3e, lane 1 and lane 6 bands from the left are similar to each other"
In the "GATA-4" panel of Fig.3e, lane 1 and lane 6 bands from the left are similar to each other"
Concern#5
In Fig.3e, Lane 1 and 2 image from the left of a GATA-4 panel are a vertically flipped and resized version of lane 1 and 2 image from the left of Nkx2.5 panel.
In Fig.3e, Lane 1 and 2 image from the left of a GATA-4 panel are a vertically flipped and resized version of lane 1 and 2 image from the left of Nkx2.5 panel.
Concern#6
In Supplementary Figure S3e, the left band of "Nkx2.5 (-)" panel is the same as the right band of "GATA4 BP4-2" panel.
Concern#7
In Supplementary Figure S3f, the left band of beta-actin panel is a resized version of that of Nkx2.5 panel.
In Supplementary Figure S3f, the left band of beta-actin panel is a resized version of that of Nkx2.5 panel.
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